Trafficking of HIV1 RNA is mediated by heterogeneous nuclear ribonucleoprotein A2 expression and impacts on viral assembly

K Lévesque, M Halvorsen, L Abrahamyan… - Traffic, 2006 - Wiley Online Library
… The role of hnRNP A2 during the expression of a bona fide provirus in HeLa … of hnRNP A2
expression in HIV-1-expressing cells results in the rapid accumulation of HIV-1 genomic RNA

[HTML][HTML] … (HIV-1) induces the cytoplasmic retention of heterogeneous nuclear ribonucleoprotein A1 by disrupting nuclear import: implications for HIV-1 gene expression

A Monette, L Ajamian, M López-Lastra… - Journal of Biological …, 2009 - ASBMB
… of hnRNP A1 positively regulates HIV-1 IRES-mediated vRNA … RNP due to nuclear pore
complex disruption, an effect that … according to the manufacturer's instructions. To calculate IRES …

RNA trafficking signals in human immunodeficiency virus type 1

AJ Mouland, H Xu, H Cui, W Krueger… - … and cellular biology, 2001 - Taylor & Francis
RNA trafficking in targeting HIV gene expression is discussed. … We identify two separate
A2RE-like sequences in the HIV-1 … Intracellular RNA trafficking could potentially affect various …

[HTML][HTML] Diverse roles of heterogeneous nuclear ribonucleoproteins in viral life cycle

K Bhattarai, M Holcik - Frontiers in Virology, 2022 - frontiersin.org
… of hnRNP D have differential effects on HIV-1 Gag expression… it to the plasma membrane for
virion assembly (177, 192, 193)… hnRNPs involvement on viral RNA trafficking and packaging …

Trafficking of HIV-1 RNA: recent progress involving host cell RNABinding proteins

AJ Mouland, ÉA Cohen, L DesGroseillers - Current Genomics, 2003 - ingentaconnect.com
… to select regions of the cell and has functional consequences … , heterogenous nuclear
ribonucleoprotein A2 (hnRNP A2) … role in RNA trafficking and the control of HIV-1 gene …

Genome-wide analysis of heterogeneous nuclear ribonucleoprotein (hnRNP) binding to HIV-1 RNA reveals a key role for hnRNP H1 in alternative viral mRNA splicing

SB Kutluay, A Emery, SR Penumutchu… - Journal of …, 2019 - Am Soc Microbiol
… Notably, HIV-1 infection may prevent the assembly of stress … the RNAi-mediated knockdown
of hnRNPs might alter HIV-1 … of hnRNP H1 binding sites would affect viral gene expression. …

Retroviral hijacking of host transport pathways for genome nuclear export

RT Behrens, NM Sherer - Mbio, 2023 - Am Soc Microbiol
… or induction of virus-induced cell stresses that otherwise impact the … (110) linked HIV-1 RNA
trafficking to intracellular … of HIV-1 Rev and its primary role in HIV-1 gene expression, it was …

Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2

M Kane, SV Rebensburg, MA Takata, TM Zang… - Elife, 2018 - elifesciences.org
… HeLa and HT1080 cell lines that expressed MX2 in a doxycycline-… effects of MX2, cell cycle
arrest, and CypA/CsA on HIV-1trafficking both within and between cells that influences viral

hnRNP A2 is a protein involved in the trafficking pathway of HIV-1 genomic RNA

K Lévesque - 2005 - escholarship.mcgill.ca
… identified heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) … of hnRNP A2 in the
trafficking, protein expression was … RNA and the impact on RNA localization, protein expression

Viral subversion of nucleocytoplasmic trafficking

ML Yarbrough, MA Mata, R Sakthivel, BMA Fontoura - Traffic, 2014 - Wiley Online Library
… , which is an effect that likely contributes to viral infection. … translation of viral mRNAs while
the expression and trafficking of … HIV-1 encodes the Rev protein that interacts with these viral